PDB Generated by OpenFold3
PDB Generated by OpenFold3
contigs stands for contiguous [protein regions].
contigs stands for contiguous [protein regions].
The hotspot residues string provides a way to specify which region the new protein (binder) must contact with the original input protein (a target), therefore we can guide a binder to a specific region.
The hotspot residues string provides a way to specify which region the new protein (binder) must contact with the original input protein (a target), therefore we can guide a binder to a specific region.
PDB Generated by RF Diffusion
PDB Generated by RF Diffusion
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1. Use of the RfDiffusion NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for AI Products. Use of the model is governed by the NVIDIA AI Foundation Models Community License Agreement. Additional Information: BSD license.
2. Use of the ProteinMPNN NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for NVIDIA AI Products. Use of the model is governed by the NVIDIA Community Model License. ADDITIONAL INFORMATION: MIT License.
3. Use of the OpenFold3 NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for NVIDIA AI Products. Use of the model is governed by the NVIDIA Open Model License. ADDITIONAL INFORMATION: Apache 2.0.

This blueprint shows how generative AI and accelerated NIM microservices can design protein binders smarter and faster.