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Input
AlphaFold2 InputsChoose an example to get started.
Binder Design Amino acid sequence input selection
Choose which cached model you want to use for this blueprint
Amino Acid Sequence
For interactivity, the sequence of the target protein cannot be edited, but stay tuned
RFDiffusion InputsComplete this form to generate a Protein file that will be used in ProteinMPNN in this Blueprint.
PDB Generated by Alphafold2
contigs stands for contiguous [protein regions].
The hotspot residues string provides a way to specify which region the new protein (binder) must contact with the original input protein (a target), therefore we can guide a binder to a specific region.
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ProteinMPNN InputsChoose how the protein target will be sent to ProteinMPNN.
PDB Generated by RF Diffusion
Chose a model option
0.01
0.11
0.21
0.31
0.41
0.51
0.61
0.71
0.81
0.91
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Using free API for development
GOVERNING TERMS: Your use of this API is governed by the NVIDIA API Trial Service Terms of Use; and the use of this blueprint is governed by the NVIDIA AI Foundation Models Community License.
Output
Click Design ProteinAdjust the settings and click Design Protein to see your outcome here.
