nvidia
Build A Generative Protein Binder Design Pipeline
EnterpriseThis blueprint shows how generative AI and accelerated NIM microservices can design protein binders smarter and faster.
Input
PDB Generated by OpenFold3
PDB Generated by OpenFold3
contigs stands for contiguous [protein regions].
contigs stands for contiguous [protein regions].
The hotspot residues string provides a way to specify which region the new protein (binder) must contact with the original input protein (a target), therefore we can guide a binder to a specific region.
The hotspot residues string provides a way to specify which region the new protein (binder) must contact with the original input protein (a target), therefore we can guide a binder to a specific region.
PDB Generated by RF Diffusion
PDB Generated by RF Diffusion
GOVERNING HOSTING TERMS: Use of this trial service is governed by the NVIDIA API Trial Terms of Service. Use of this blueprint software is governed by the Apache 2.0, and enables use of separate open source and proprietary software, models, data and services governed by their respective licenses below:
1. Use of the RfDiffusion NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for AI Products. Use of the model is governed by the NVIDIA AI Foundation Models Community License Agreement. Additional Information: BSD license.
2. Use of the ProteinMPNN NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for NVIDIA AI Products. Use of the model is governed by the NVIDIA Community Model License. ADDITIONAL INFORMATION: MIT License.
3. Use of the OpenFold3 NIM is governed by the NVIDIA Software License Agreement and Product-Specific Terms for NVIDIA AI Products. Use of the model is governed by the NVIDIA Open Model License. ADDITIONAL INFORMATION: Apache 2.0.