AlphaFold2 InputsChoose an example to get started.

Cached AlphaFold2 folded proteins

Choose which cached model you want to use for this blueprint

Amino Acid Sequence*

For interactivity, the sequence of the target protein cannot be edited, but stay tuned

RFDiffusion InputsComplete this form to generate a Protein file that will be used in ProteinMPNN in this Blueprint.

Target Protein

Contigs*

Hotspot Residues

Diffusion Steps

ProteinMPNN InputsChoose how the protein target will be sent to ProteinMPNN.

Target Protein

Model

Sampling Temperature

0.01

0.11

0.21

0.31

0.41

0.51

0.61

0.71

0.81

0.91

GOVERNING TERMS: Your use of this API is governed by the NVIDIA API Trial Service Terms of Use; and the use of this blueprint is governed by the NVIDIA AI Foundation Models Community License.

Click Design ProteinAdjust the settings and click Design Protein to see your outcome here.

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Build A Generative Protein Binder Design Pipeline

This blueprint shows how generative AI and accelerated NIM microservices can design protein binders smarter and faster.