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Biology

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Explore NVIDIA Blueprints

Comprehensive reference workflows that accelerate application development and deployment, featuring NVIDIA acceleration libraries, APIs, and microservices for AI agents, digital twins, and more.

nvidiaBuild A Generative Protein Binder Design Pipeline

This blueprint shows how generative AI and accelerated NIM microservices can design protein binders smarter and faster.

BioNemoBiologyProtein Generation

nvidiaBuild A Generative Virtual Screening Pipeline

This blueprint shows how generative AI and accelerated NIM microservices can design optimized small molecules smarter and faster.

BioNemoChemistryDockingNIM

Generative Virtual Screening

Search a library of small molecules to identify chemical structures which are most likely to bind to a target protein.

NVIDIA
Downloadable

genmol

Fragment-Based Molecular Generation by Discrete Diffusion.
BioNemo
ChemistryMolecule Generationnim
6K API calls in the last 30 days
Last updated on July 21, 2025
MIT
Downloadable

diffdock

Predicts the 3D structure of how a molecule interacts with a protein.
BioNemo
ChemistryDockingnim
Last updated on July 15, 2025
NVIDIA
Downloadable

molmim

MolMIM performs controlled generation, finding molecules with the right properties.
BioNemo
ChemistryMolecule Generationnim
Last updated on July 18, 2025
Openfold
Downloadable

openfold3

OpenFold3 is a third-generation biomolecular foundation model that predicts the three-dimensional structures of molecular complexes (proteins, DNA, RNA, ligands)
Biology
Protein Folding
82K API calls in the last 30 days
Last updated on October 24, 2025
MIT
Downloadable

Boltz-2

Predict complex structures using Boltz-2.
Biology
BionemoProtein Foldingnim
Last updated on July 9, 2025
Meta
Free Endpoint

esmfold

Predicts the 3D structure of a protein from its amino acid sequence.
Bionemo
Drug Discoverybiologynimprotein folding
566K API calls in the last 30 days
Last updated on June 12, 2025
Colabfold
Downloadable

msa-search

Generates a multiple sequence alignment from a query sequence and a protein sequence database search.
Biology
BionemoProtein Foldingnim
Last updated on June 16, 2025
Openfold
Downloadable

openfold2

Predicts the 3D structure of a protein from its amino acid sequence, multiple sequence alignments, and templates.
Biology
BionemoProtein Foldingnim
Last updated on May 29, 2025
DeepMind
Downloadable

alphafold2

Predicts the 3D structure of a protein from its amino acid sequence.
Biology
Bionemonimprotein folding
194 API calls in the last 30 days
Last updated on March 22, 2025
DeepMind
Downloadable

alphafold2-multimer

Predicts the 3D structure of a protein from its amino acid sequence.
Biology
Bionemonimprotein folding
61 API calls in the last 30 days
Last updated on March 22, 2025

Protein Structure Prediction

Predict three-dimensional structure of a protein or complex from its amino acid sequence.

Protein Design

Generate a new protein structure that binds to a target protein.

Arc
Downloadable

evo2-40b

Evo 2 is a biological foundation model that is able to integrate information over long genomic sequences while retaining sensitivity to single-nucleotide changes.
Bionemo
DNA Generationbiologynim
88K API calls in the last 30 days
Last updated on May 28, 2025
IPD
Downloadable

rfdiffusion

A generative model of protein backbones for protein binder design.
BioNemo
Protein Generationbiologynim
7K API calls in the last 30 days
Last updated on May 28, 2025
IPD
Downloadable

proteinmpnn

ProteinMPNN is a deep learning model for predicting amino acid sequences for protein backbones.
BioNemo
Protein Generationbiologynim
5K API calls in the last 30 days
Last updated on July 22, 2025
Meta
Free Endpoint

esm2-650m

Generates embeddings of proteins from their amino acid sequences.
BioNemo
BiologyProtein Embeddingnim
128K API calls in the last 30 days
Last updated on March 10, 2025